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The Probiotic of Choice: Florastor is the number 1 probiotic in its class around the world; We use a unique and effective probiotic strain with over 65 years of use and research. – Antibiotic Resistant: Our resilient probiotic formula thrives even during antibiotic use, with proven resistance to 16 of the most common oral antibiotics; No refrigeration required, 3-year shelf life.